HEALTH ?Midlife Coffee And Tea Drinking may reduce risk of Dementia
MILAN - Drinking coffee in the middle stages of life could decrease the risk of dementia/Alzheimer's disease (AD) later in life. This conclusion is made in a Finnish Cardiovascular Risk Factors, Aging and Dementia (Caide) Study published in the Journal of Alzheimer's Disease.
This study has been conducted at the University of Kuopio, Finland in collaboration with Karolinska Institutet, Stockholm, Sweden, and the National Public Health Institute, Helsinki, Finland.
The study included participants from the survivors of population-based cohorts previously surveyed within the North Karelia Project and the FINMONICA study in 1972, 1977, 1982 or 1987 (midlife visit). After an average follow-up of 21 years, 1409 individuals (71%) aged 65 to 79 completed the re-examination in1998. A total of 61 cases were identified as demented (48 with AD).
The research found that those who drink coffee in midlife have a lower risk for late-onset dementia and Alzheimer's disease compared to those who drink little or no coffee.
Researchers found the lowest risk among moderate coffee drinkers, or those who drank three to five cups a day. Their dementia or Alzheimer's risk was lowered by 65%.
While tea drinking did not appear to lower the risk of dementia or Alzheimer's, it did not increase the risk for either condition.
"We aimed to study the association between coffee and tea consumption at midlife and dementia/AD risk in late-life, because the long-term impact of caffeine on the central nervous system was still unknown, and as the pathologic processes leading to Alzheimer's disease may start decades before the clinical manifestation of the disease," says lead researcher, associate professor Miia Kivipelto, from the University of Kuopio, Finland and Karolinska Institutet, Stockholm, Sweden.
""Given the large amount of coffee consumption globally, the results might have important implications for the prevention of or delaying the onset of dementia or Alzheimer's disease," Kivipelto also said "The finding needs to be confirmed by other studies, but it opens the possibility that dietary interventions could modify the risk of dementia and Alzheimer's disease. Also, identification of mechanisms of how coffee exerts its protection against dementia/AD might help in the development of new therapies for these diseases."
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